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Enhancement of solubility of Mebendazole by SEDDS | Self Emulsifying Drug Delivery System of Mebendazole with improved solubility, effective against lymphatic filariasis | Naveen Patel (u. a.) | Buch - Patel, Naveen
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Enhancement of solubility of Mebendazole by SEDDS | Self Emulsifying Drug Delivery System of Mebendazole with improved solubility, effective against lymphatic filariasis | Naveen Patel (u. a.) | Buch - edizione con copertina flessibile

2012, ISBN: 9783659116339

[ED: Taschenbuch], [PU: LAP Lambert Academic Publishing], The aim of the present work was to prepare Self emulsifying drug delivery system (SEDDS) of a lipophilic drug, Mebendazole for in… Altro …

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Enhancement of solubility of Mebendazole by SEDDS / Self Emulsifying Drug Delivery System of Mebendazole with improved solubility, effective against lymphatic filariasis / Naveen Patel (u. a.) / Buch - Patel, Naveen
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Patel, Naveen:

Enhancement of solubility of Mebendazole by SEDDS / Self Emulsifying Drug Delivery System of Mebendazole with improved solubility, effective against lymphatic filariasis / Naveen Patel (u. a.) / Buch - edizione con copertina flessibile

2012, ISBN: 9783659116339

[ED: Taschenbuch], [PU: LAP Lambert Academic Publishing], The aim of the present work was to prepare Self emulsifying drug delivery system (SEDDS) of a lipophilic drug, Mebendazole for in… Altro …

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Enhancement of solubility of Mebendazole by SEDDS - Naveen Patel|Aparna Lanka
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Enhancement of solubility of Mebendazole by SEDDS - edizione con copertina flessibile

2012

ISBN: 3659116335

[EAN: 9783659116339], Neubuch, [PU: LAP LAMBERT Academic Publishing], MEDIZIN PHARMAZIE MEBENDAZOLE SELF EMULSIFYING DRUG DELIVERY TOCOPHEROL ACETATE PEG 200 LABRASOL, Dieser Artikel ist … Altro …

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Enhancement of solubility of Mebendazole by SEDDS - Naveen Patel Aparna Lanka
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Enhancement of solubility of Mebendazole by SEDDS - copertina rigida, flessible

2012, ISBN: 9783659116339

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Lanka, Aparna,Patel, Naveen:
Enhancement of solubility of Mebendazole by SEDDS: Self Emulsifying Drug Delivery System of Mebendazole with improved solubility, effective against lymphatic filariasis - edizione con copertina flessibile

2012, ISBN: 9783659116339

LAP LAMBERT Academic Publishing, 2012-06-23. Paperback. Good. 0.7480 in x 8.4252 in x 5.8661 in., LAP LAMBERT Academic Publishing, 2012-06-23, 2.5

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Enhancement of solubility of Mebendazole by SEDDS: Self Emulsifying Drug Delivery System of Mebendazole with improved solubility, effective against lymphatic filariasis
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ISBN:

3659116335


The aim of the present work was to prepare Self emulsifying drug delivery system (SEDDS) of a lipophilic drug, Mebendazole for increasing its solubility. Various oils, surfactants and co-surfactants were screened for their suitability in the formulation of SEDDS. Based on the initial screening, Omix of Tocopherol acetate and Peceol in the ratio 6:4 and surfactant, Labrasol and co-surfactant, PEG 200 were found to be satisfactory. Five formulations were selected from pseudoternary phase diagrams and were evaluated for parameters like drug content, percentage transmittance, dilution potential, centrifugation test, in-vitro release study, emulsification time and dispersibility, emulsion droplet size, zeta potential, polydispersibility index and ex-vivo permeation studies. All the formulations exhibited a rapid emulsification rate and a good polydispersibity index. The size of the droplets as determined by zeta sizer was found to be below 300 nm. The percentage drug release from the formulations was improved compared to that of pure drug. Thus, the formulated SEDDS helped in improving the solubility and dissolution of the drug, thereby increasing its therapeutic effectiveness.

Informazioni dettagliate del libro - Enhancement of solubility of Mebendazole by SEDDS: Self Emulsifying Drug Delivery System of Mebendazole with improved solubility, effective against lymphatic filariasis


EAN (ISBN-13): 9783659116339
ISBN (ISBN-10): 3659116335
Copertina rigida
Copertina flessibile
Anno di pubblicazione: 2012
Editore: LAP LAMBERT Academic Publishing

Libro nella banca dati dal 2008-12-03T11:42:46+01:00 (Zurich)
Pagina di dettaglio ultima modifica in 2023-11-08T21:02:57+01:00 (Zurich)
ISBN/EAN: 3659116335

ISBN - Stili di scrittura alternativi:
3-659-11633-5, 978-3-659-11633-9
Stili di scrittura alternativi e concetti di ricerca simili:
Autore del libro : patel, lanka
Titolo del libro: solubilities, enhancement, solubility

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