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Lena Daumanns''s thesis describes structural and functional studies of the enzyme Glycerophosphodiesterase (GpdQ) from Enterobacter aerogenes. It also examines the properties of small mim… Altro …

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Spectroscopic and Mechanistic Studies of Dinuclear Metallohydrolases and Their Biomimetic Complexes (Springer Theses) - copertina rigida, flessible

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Springer, Gebundene Ausgabe, Auflage: 2014, 260 Seiten, Publiziert: 2014-06-13T00:00:01Z, Produktgruppe: Buch, Hersteller-Nr.: 178 black & white illustrations, 22 colo, 11.48 kg, Chemie, … Altro …

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Daumann, Lena Josefine:
Spectroscopic and Mechanistic Studies of Dinuclear Metallohydrolases and Their Biomimetic Complexes (Springer Theses) - copertina rigida, flessible

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ISBN: 9783319066288

Springer, Gebundene Ausgabe, Auflage: 2014, 260 Seiten, Publiziert: 2014-06-13T00:00:01Z, Produktgruppe: Buch, Hersteller-Nr.: 178 black & white illustrations, 22 colo, 11.48 kg, Chemie, … Altro …

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Spectroscopic and Mechanistic Studies of Dinuclear Metallohydrolases and Their Biomimetic Complexes - copertina rigida, flessible

2014, ISBN: 3319066285

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Spectroscopic and Mechanistic Studies of Dinuclear Metallohydrolases and Their Biomimetic Complexes by Lena Josefine Daumann Hardcover | Indigo Chapte
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Titolo:
ISBN:

9783319066288


Lena Daumanns's thesis describes structural and functional studies of the enzyme Glycerophosphodiesterase (GpdQ) from Enterobacter aerogenes. It also examines the properties of small mimics of this enzyme and related binuclear metallohydrolases such as the metallo-ss-lactamases to enhance our understanding of hydrolytic cleavage of important substrates like phosphoesters and ss-lactams. Overall, this project has led to a better understanding of the metal ion binding and active site structural features of the enzyme GpdQ. Daumann describes how she successfully immobilized phosphoesterase and related biomimetics on solid supports for potential applications in the area of bioremediation of organophosphate pesticides. Analysis shows that both the enzyme and biomimetics can be stored on the solid support without loss of activity. Furthermore, the author specroscopically and mechanistically characterized a number of Zn(II), Cd(II) and Co(II) complexes, some of which are among the most active biomimetics towards organophosphates reported to date. This thesis makes excellent reading for non-specialists because each chapter includes a short introduction section.

Informazioni dettagliate del libro - Spectroscopic and Mechanistic Studies of Dinuclear Metallohydrolases and Their Biomimetic Complexes by Lena Josefine Daumann Hardcover | Indigo Chapte


EAN (ISBN-13): 9783319066288
ISBN (ISBN-10): 3319066285
Copertina rigida
Anno di pubblicazione: 2014
Editore: Lena Josefine Daumann

Libro nella banca dati dal 2014-10-18T18:20:46+02:00 (Zurich)
Pagina di dettaglio ultima modifica in 2023-06-02T12:33:29+02:00 (Zurich)
ISBN/EAN: 9783319066288

ISBN - Stili di scrittura alternativi:
3-319-06628-5, 978-3-319-06628-8
Stili di scrittura alternativi e concetti di ricerca simili:
Autore del libro : daum, dau, daumann
Titolo del libro: springer theses

Dati dell'editore

Autore: Lena Josefine Daumann
Titolo: Springer Theses; Spectroscopic and Mechanistic Studies of Dinuclear Metallohydrolases and Their Biomimetic Complexes
Editore: Springer; Springer International Publishing
239 Pagine
Anno di pubblicazione: 2014-06-13
Cham; CH
Stampato / Fatto in
Lingua: Inglese
106,99 € (DE)
109,99 € (AT)
118,00 CHF (CH)
POD
XXI, 239 p. 200 illus., 22 illus. in color.

BB; Hardcover, Softcover / Technik/Chemische Technik; Biotechnologie; Verstehen; Antibiotic Resistance; Bioinspired Hydrolysis; Biomimetic Complex; Dinuclear Cobalt Complexes Magnetism; Magnetic Circular Dichrosim; Metallo-beta-lactamase; Organophosphate Pesticide Bioremediation; Phosphoesterase Enzymes; biochemical engineering; Chemical Bioengineering; Enzymology; Spectroscopy; Chemische Biologie; Spektroskopie, Spektrochemie, Massenspektrometrie; EA; BC

Lena Daumanns's thesis describes structural and functional studies of the enzyme Glycerophosphodiesterase (GpdQ) from Enterobacter aerogenes. It also examines the properties of small mimics of this enzyme and related binuclear metallohydrolases such as the metallo-ß-lactamases to enhance our understanding of hydrolytic cleavage of important substrates like phosphoesters and β-lactams. Overall, this project has led to a better understanding of the metal ion binding and active site structural features of the enzyme GpdQ. Daumann describes how she successfully immobilized phosphoesterase and related biomimetics on solid supports for potential applications in the area of bioremediation of organophosphate pesticides. Analysis shows that both the enzyme and biomimetics can be stored on the solid support without loss of activity. Furthermore, the author specroscopically and mechanistically characterized a number of Zn(II), Cd(II) and Co(II) complexes, some of which are among the most active biomimetics towards organophosphates reported to date. This thesis makes excellent reading for non-specialists because each chapter includes a short introduction section.
Nominated as an Outstanding Ph.D. thesis by the University of Queensland, Australia Encompasses a broad range of topics including biochemical, kinetic and mechanistic studies, chemical synthesis, as well as the use of polymeric and nanoparticle supports Enhances our understanding of hydrolytic cleavage of important substrates like phosphoesters and ß-lactams Includes a short introduction to each chapter to guide non-specialist readers Includes supplementary material: sn.pub/extras
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