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Fluid Dynamics of a Centrifugal Left Ventricular Assist Device - High-shear Regions and Implications for von Willebrand Factor and Endothelialization - Selgrade, Brian
libro esaurito
(*)
Selgrade, Brian:
Fluid Dynamics of a Centrifugal Left Ventricular Assist Device - High-shear Regions and Implications for von Willebrand Factor and Endothelialization - edizione con copertina flessibile

2011, ISBN: 9783639360998

[ED: Taschenbuch / Paperback], [PU: VDM Verlag Dr. MÃller], High shear stresses and shear rates in left ventricular assist devices (LVADs) make endothelialization of the LVAD difficult and likely contribute to cleavage of large von Willebrand factor multimers and resulting bleeding problems in patients. To better understand shear in a centrifugal LVAD, flow was simulated using finite volume and computational fluid dynamics (CFD) analysis. The k- model simulated turbulence and sliding meshes were used to model the movement of the impeller. CFD results showed high-shear backflows in the radial gap between the impeller and the volute wall, but residence times in this region were under 5ms. It is unclear if this is sufficient to cleave VWF, and more study is necessary to determine if other areas in the LVAD have potential for VWF cleavage. Although the walls near the outlet experience low shear stress and may be good candidates for endothelialization, shear stresses above 20-30Pa on all other walls of the pump make the possibility of endothelial cell growth elsewhere in the LVAD unlikely. An LVAD designed specifically to have low shear may be a better candidate for endothelialization., DE, [SC: 0.00], Neuware, gewerbliches Angebot, H: 221mm, B: 152mm, T: 10mm, 100, [GW: 152g], Selbstabholung und Barzahlung, PayPal, offene Rechnung, Banküberweisung, Interntationaler Versand

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(*) Libro esaurito significa che il libro non è attualmente disponibile in una qualsiasi delle piattaforme associate che di ricerca.
Fluid Dynamics of a Centrifugal Left Ventricular Assist Device - High-shear Regions and Implications for von Willebrand Factor and Endothelialization - Selgrade, Brian
libro esaurito
(*)
Selgrade, Brian:
Fluid Dynamics of a Centrifugal Left Ventricular Assist Device - High-shear Regions and Implications for von Willebrand Factor and Endothelialization - edizione con copertina flessibile

2011, ISBN: 9783639360998

[ED: Taschenbuch / Paperback], [PU: VDM Verlag Dr. MÃller], High shear stresses and shear rates in left ventricular assist devices (LVADs) make endothelialization of the LVAD difficult and likely contribute to cleavage of large von Willebrand factor multimers and resulting bleeding problems in patients. To better understand shear in a centrifugal LVAD, flow was simulated using finite volume and computational fluid dynamics (CFD) analysis. The k- model simulated turbulence and sliding meshes were used to model the movement of the impeller. CFD results showed high-shear backflows in the radial gap between the impeller and the volute wall, but residence times in this region were under 5ms. It is unclear if this is sufficient to cleave VWF, and more study is necessary to determine if other areas in the LVAD have potential for VWF cleavage. Although the walls near the outlet experience low shear stress and may be good candidates for endothelialization, shear stresses above 20-30Pa on all other walls of the pump make the possibility of endothelial cell growth elsewhere in the LVAD unlikely. An LVAD designed specifically to have low shear may be a better candidate for endothelialization., DE, [SC: 0.00], Neuware, gewerbliches Angebot, H: 221mm, B: 152mm, T: 10mm, 100, [GW: 152g], Selbstabholung und Barzahlung, PayPal, offene Rechnung, Banküberweisung, Internationaler Versand

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Fluid Dynamics of a Centrifugal Left Ventricular Assist Device - High-shear Regions and Implications for von Willebrand Factor and Endothelialization
libro esaurito
(*)
Fluid Dynamics of a Centrifugal Left Ventricular Assist Device - High-shear Regions and Implications for von Willebrand Factor and Endothelialization - edizione con copertina flessibile

2011, ISBN: 9783639360998

[ED: Taschenbuch / Paperback], [PU: VDM Verlag Dr. Müller], High shear stresses and shear rates in left ventricular assist devices (LVADs) make endothelialization of the LVAD difficult and likely contribute to cleavage of large von Willebrand factor multimers and resulting bleeding problems in patients. To better understand shear in a centrifugal LVAD, flow was simulated using finite volume and computational fluid dynamics (CFD) analysis. The k- model simulated turbulence and sliding meshes were used to model the movement of the impeller. CFD results showed high-shear backflows in the radial gap between the impeller and the volute wall, but residence times in this region were under 5ms. It is unclear if this is sufficient to cleave VWF, and more study is necessary to determine if other areas in the LVAD have potential for VWF cleavage. Although the walls near the outlet experience low shear stress and may be good candidates for endothelialization, shear stresses above 20-30Pa on all other walls of the pump make the possibility of endothelial cell growth elsewhere in the LVAD unlikely. An LVAD designed specifically to have low shear may be a better candidate for endothelialization., [SC: 0.00], Neuware, gewerbliches Angebot

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Fluid Dynamics of a Centrifugal Left Ventricular Assist Device - Brian Selgrade
libro esaurito
(*)
Brian Selgrade:
Fluid Dynamics of a Centrifugal Left Ventricular Assist Device - nuovo libro

ISBN: 9783639360998

ID: 1294fdf8f39eceb6a8997cbd5f4278bb

High shear stresses and shear rates in left ventricular assist devices (LVADs) make endothelialization of the LVAD difficult and likely contribute to cleavage of large von Willebrand factor multimers and resulting bleeding problems in patients. To better understand shear in a centrifugal LVAD, flow was simulated using finite volume and computational fluid dynamics (CFD) analysis. The k- model simulated turbulence and sliding meshes were used to model the movement of the impeller. CFD results showed high-shear backflows in the radial gap between the impeller and the volute wall, but residence times in this region were under 5ms. It is unclear if this is sufficient to cleave VWF, and more study is necessary to determine if other areas in the LVAD have potential for VWF cleavage. Although the walls near the outlet experience low shear stress and may be good candidates for endothelialization, shear stresses above 20-30Pa on all other walls of the pump make the possibility of endothelial cell growth elsewhere in the LVAD unlikely. An LVAD designed specifically to have low shear may be a better candidate for endothelialization. Bücher / Naturwissenschaften, Medizin, Informatik & Technik / Medizin, [PU: VDM Verlag Dr. Müller, Saarbrücken]

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Fluid Dynamics of a Centrifugal Left Ventricular Assist Device - Selgrade, Brian
libro esaurito
(*)
Selgrade, Brian:
Fluid Dynamics of a Centrifugal Left Ventricular Assist Device - edizione con copertina flessibile

2011, ISBN: 9783639360998

[ED: Softcover], [PU: Vdm Verlag Dr. Müller], High shear stresses and shear rates in left ventricular assist devices (LVADs) make endothelialization of the LVAD difficult and likely contribute to cleavage of large von Willebrand factor multimers and resulting bleeding problems in patients. To better understand shear in a centrifugal LVAD, flow was simulated using finite volume and computational fluid dynamics (CFD) analysis. The k- model simulated turbulence and sliding meshes were used to model the movement of the impeller. CFD results showed high-shear backflows in the radial gap between the impeller and the volute wall, but residence times in this region were under 5ms. It is unclear if this is sufficient to cleave VWF, and more study is necessary to determine if other areas in the LVAD have potential for VWF cleavage. Although the walls near the outlet experience low shear stress and may be good candidates for endothelialization, shear stresses above 20-30Pa on all other walls of the pump make the possibility of endothelial cell growth elsewhere in the LVAD unlikely. An LVAD designed specifically to have low shear may be a better candidate for endothelialization.2011. 100 S. 221 mmVersandfertig in 3-5 Tagen, [SC: 0.00]

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Dettagli del libro
Fluid Dynamics of a Centrifugal Left Ventricular Assist Device

High shear stresses and shear rates in left ventricular assist devices (LVADs) make endothelialization of the LVAD difficult and likely contribute to cleavage of large von Willebrand factor multimers and resulting bleeding problems in patients. To better understand shear in a centrifugal LVAD, flow was simulated using finite volume and computational fluid dynamics (CFD) analysis. The k-¿ model simulated turbulence and sliding meshes were used to model the movement of the impeller. CFD results showed high-shear backflows in the radial gap between the impeller and the volute wall, but residence times in this region were under 5ms. It is unclear if this is sufficient to cleave VWF, and more study is necessary to determine if other areas in the LVAD have potential for VWF cleavage. Although the walls near the outlet experience low shear stress and may be good candidates for endothelialization, shear stresses above 20-30Pa on all other walls of the pump make the possibility of endothelial cell growth elsewhere in the LVAD unlikely. An LVAD designed specifically to have low shear may be a better candidate for endothelialization.

Informazioni dettagliate del libro - Fluid Dynamics of a Centrifugal Left Ventricular Assist Device


EAN (ISBN-13): 9783639360998
ISBN (ISBN-10): 3639360990
Copertina rigida
Copertina flessibile
Anno di pubblicazione: 2011
Editore: VDM Verlag

Libro nella banca dati dal 29.10.2007 15:15:21
libro trovato per l'ultima volta il21.10.2017 10:27:19
ISBN/EAN: 9783639360998

ISBN - Stili di scrittura alternativi:
3-639-36099-0, 978-3-639-36099-8


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