2009, ISBN: 9781603272667

[ED: Gebunden], [PU: Humana Press], Chemokines are a superfamily of low molecular weight cytokines that were initially described based on their ability to induce the directed migration of… Altro …

[ED: Gebunden], [PU: Humana Press], Chemokines are a superfamily of low molecular weight cytokines that were initially described based on their ability to induce the directed migration of leukocytes to sites of inflammation or injury. In humans, there are approximately 45 chemokines that bind to 19 G-protein-coupled receptors. In addition to mediating cellular migration, chemokines have now been shown to affect many cellular functions including survival, adhesion, invasion, proliferation, and to regulate circulating chemokine levels. Although chemokine receptors were first described on leukocytes, it is now appreciated that chemokine receptors are also expressed by many other cells including endothelial and epithelial cells.Since the first description of chemokine receptors on malignant cells in 2001, an extensive literature has developed describing the expression and function of chemokine receptors in many malignancies. These studies support the initial hypothesis that malignant cells use chemokine receptors to migrate to distant sites of ligand expression and that expression of certain receptors is associated with a poor prognosis. It has also become apparent that malignancies of different tissues may use a diverse profile of chemokine receptors and that the same receptor may mediate metastasis to different sites in tumors of different histological origins. Receptor function may also maintain survival and expansion of the primary tumor., DE, [SC: 0.00], Neuware, gewerbliches Angebot, 172, [GW: 446g], Sofortüberweisung, PayPal, Banküberweisung<

2009, ISBN: 9781603272667

Chemokines are a superfamily of low molecular weight cytokines that were initially described based on their ability to induce the directed migration of leukocytes to sites of inflammation… Altro …

Chemokines are a superfamily of low molecular weight cytokines that were initially described based on their ability to induce the directed migration of leukocytes to sites of inflammation or injury. In humans, there are approximately 45 chemokines that bind to 19 G-protein-coupled receptors. In addition to mediating cellular migration, chemokines have now been shown to affect many cellular functions including survival, adhesion, invasion, proliferation, and to regulate circulating chemokine levels. Although chemokine receptors were first described on leukocytes, it is now appreciated that chemokine receptors are also expressed by many other cells including endothelial and epithelial cells. Since the first description of chemokine receptors on malignant cells in 2001, an extensive literature has developed describing the expression and function of chemokine receptors in many malignancies. These studies support the initial hypothesis that malignant cells use chemokine receptors to migrate to distant sites of ligand expression and that expression of certain receptors is associated with a poor prognosis. It has also become apparent that malignancies of different tissues may use a diverse profile of chemokine receptors and that the same receptor may mediate metastasis to different sites in tumors of different histological origins. Receptor function may also maintain survival and expansion of the primary tumor. Buch (fremdspr.) Humana Press gebundene Ausgabe, Humana Press, 27.05.2009, Humana Press, 2009<

2001, ISBN: 9781603272667

Chemokines are a superfamily of low molecular weight cytokines that were initially described based on their ability to induce the directed migration of leukocytes to sites of inflammation… Altro …

Chemokines are a superfamily of low molecular weight cytokines that were initially described based on their ability to induce the directed migration of leukocytes to sites of inflammation or injury. In humans, there are approximately 45 chemokines that bind to 19 G-protein-coupled receptors. In addition to mediating cellular migration, chemokines have now been shown to affect many cellular functions including survival, adhesion, invasion, proliferation, and to regulate circulating chemokine levels. Although chemokine receptors were first described on leukocytes, it is now appreciated that chemokine receptors are also expressed by many other cells including endothelial and epithelial cells. Since the first description of chemokine receptors on malignant cells in 2001, an extensive literature has developed describing the expression and function of chemokine receptors in many malignancies. These studies support the initial hypothesis that malignant cells use chemokine receptors to migrate to distant sites of ligand expression and that expression of certain receptors is associated with a poor prognosis.It has also become apparent that malignancies of different tissues may use a diverse profile of chemokine receptors and that the same receptor may mediate metastasis to different sites in tumors of different histological origins. Receptor function may also maintain survival and expansion of the primary tumor.; Health, Family & Lifestyle, Humana Press<

2009, ISBN: 1603272666

[EAN: 9781603272667], Neubuch, [PU: Humana Press], KREBS (KRANKHEIT) THERAPIE (DIVERSE) ONKOLOGIE - RADIOONKOLOGIE FORSCHUNG (MEDIZINISCH, PSYCHOLOGISCH) HEILKUNDE HUMANMEDIZIN MEDIZIN AR… Altro …

[EAN: 9781603272667], Neubuch, [PU: Humana Press], KREBS (KRANKHEIT) THERAPIE (DIVERSE) ONKOLOGIE - RADIOONKOLOGIE FORSCHUNG (MEDIZINISCH, PSYCHOLOGISCH) HEILKUNDE HUMANMEDIZIN MEDIZIN ARZNEI ARZNEIMITTELLEHRE PHARMAKOLOGIE NICHTKLINISCHE FäCHER ANGIOGENESIS CYTOKINES METASTASIS PROSTATE CANCER, Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. Cumulatively, these data indicate that chemokine receptors may serve as biomarkers of tumor behavior as well as potential therapeutic targetsIt is an appropriat, Books<

2009, ISBN: 9781603272667

edizione con copertina rigida

[ED: Gebunden], [PU: Humana Press], Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. Cumulatively, these data indicate that chemokine recep… Altro …

[ED: Gebunden], [PU: Humana Press], Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. Cumulatively, these data indicate that chemokine receptors may serve as biomarkers of tumor behavior as well as potential therapeutic targetsIt is an appropriat, DE, [SC: 0.00], Neuware, gewerbliches Angebot, Hardcover, 172, [GW: 980g], 1. Auflage, Banküberweisung, PayPal<