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Peptide-Based Drug Design / Laszlo Otvos / Buch / Methods in Molecular Biology / XI / Englisch / 2008 / SPRINGER NATURE / EAN 9781588299901 - Otvos, Laszlo
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Peptide-Based Drug Design / Laszlo Otvos / Buch / Methods in Molecular Biology / XI / Englisch / 2008 / SPRINGER NATURE / EAN 9781588299901 - copertina rigida, flessible

2008, ISBN: 9781588299901

[ED: Gebunden], [PU: SPRINGER NATURE], Due to their high specificity and low toxicity profile, peptides have once again become central to the development of new drugs. In Peptide-Based Dr… Altro …

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Peptide-Based Drug Design | Laszlo Otvos | Buch | Methods in Molecular Biology | XI | Englisch | 2008 | SPRINGER NATURE | EAN 9781588299901 - Otvos, Laszlo
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Otvos, Laszlo:

Peptide-Based Drug Design | Laszlo Otvos | Buch | Methods in Molecular Biology | XI | Englisch | 2008 | SPRINGER NATURE | EAN 9781588299901 - copertina rigida, flessible

2008, ISBN: 9781588299901

[ED: Gebunden], [PU: SPRINGER NATURE], Due to their high specificity and low toxicity profile, peptides have once again become central to the development of new drugs. In Peptide-Based Dr… Altro …

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Due to their high specificity and low toxicity profile, peptides have once again become central to the development of new drugs. In Peptide-Based Drug Design: Methods and Protocols, exper… Altro …

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Peptide-Based Drug Design (Methods in Molecular Biology, 494) - copertina rigida, flessible

ISBN: 9781588299901

Humana. Hardcover. GOOD. Spine creases, wear to binding and pages from reading. May contain limited notes, underlining or highlighting that does affect the text. Possible ex library cop… Altro …

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Peptide-Based Drug Design - copertina rigida, flessible

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Hardback, [PU: Humana Press Inc.], Due to their high specificity and low toxicity profile, peptides are once more central to the development of new drugs. Comprehensive and up-to-date, th… Altro …

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Dettagli del libro
Peptide-Based Drug Design (Methods in Molecular Biology, 494, Band 1999)
Autore:
Titolo:
ISBN:

9781588299901


Due to their high specificity and low toxicity profile, peptides have once again become central to the development of new drugs. In Peptide-Based Drug Design: Methods and Protocols, expert researchers provide a handbook which offers a selection of research and production tools suitable for transforming a promising protein fragment or stand-alone native peptide into a pharmaceutically acceptable composition. The volume delves into contemporary, cutting-edge subjects such as hit isolation and target validation, computer-aided design, sequence modifications to satisfy pharmacologists, in vivo stability and imaging, and the actual production of difficult sequences. Written in the highly successful Methods in Molecular Biology(TM) series format, chapters include readily reproducible, step-by-step laboratory protocols, lists of materials, and the Notes section, which highlights tips on troubleshooting and avoiding known pitfalls. Comprehensive and up-to-date, Peptide-Based Drug Design: Methods and Protocols shows its subject to be an independent science on the rise, and provides scientists with a clear, concise guide for continuing this vital research. TOC:Peptide-based Drug Design: Here and Now.- Strategies for the Discovery, Isolation, and Characterization of Natural Bioactive Peptides from the Immune System of Invertebrates.- Sequence Analysis of Antimicrobial Peptides by Tandem Mass Spectrometry.- The Spot Technique: Synthesis and Screening of Peptide Macroarrays on Cellulose Membranes.- Analysis of Abeta interactions using ProteinChip Technology.- NMR in Peptide Drug Development.- Molecular Dynamics Simulations of Peptides.- Short Linear Cationic Antimicrobial Peptides - Screening, Optimizing and Prediction.- Investigation of the Mode of Action of Proline-rich Antimicrobial Peptides: Genetic and Cytometric Approaches.- Serum Stability of Peptides.- Preparation of Glycosylated Amino Acids Suitable for Fmoc Solid-Phase Assembly.- Synthesis of O-Phosphopeptides on Solid Phase.- Peptidomimetics: Fmoc Solid-Phase Pseudopeptide Synthesis.- Synthesis of Toll-like Receptor-2 Targeting Lipopeptides as Self-Adjuvanting Vaccines.- Synthesis of a Multivalent, Multiepitope Vaccine Construct.- Cysteine-Containing Fusion Tag for Site-Specific Conjugation of Therapeutic and Imaging Agents to Targeting Proteins.

Informazioni dettagliate del libro - Peptide-Based Drug Design (Methods in Molecular Biology, 494, Band 1999)


EAN (ISBN-13): 9781588299901
ISBN (ISBN-10): 1588299902
Copertina rigida
Anno di pubblicazione: 2008
Editore: Otvos, Laszlo, Humana
304 Pagine
Peso: 0,610 kg
Lingua: eng/Englisch

Libro nella banca dati dal 2008-03-15T07:29:37+01:00 (Zurich)
Pagina di dettaglio ultima modifica in 2024-02-29T18:53:59+01:00 (Zurich)
ISBN/EAN: 9781588299901

ISBN - Stili di scrittura alternativi:
1-58829-990-2, 978-1-58829-990-1
Stili di scrittura alternativi e concetti di ricerca simili:
Autore del libro : laszlo, ötvös, lászló
Titolo del libro: biology 1999, design methods, molecular design, laszlo, peptide

Dati dell'editore

Autore: Laszlo Otvos
Titolo: Methods in Molecular Biology; Peptide-Based Drug Design
Editore: Humana; Humana Press
303 Pagine
Anno di pubblicazione: 2008-10-09
Totowa; NJ; US
Stampato / Fatto in
Lingua: Inglese
160,49 € (DE)
164,99 € (AT)
177,00 CHF (CH)
POD
XI, 303 p.

BB; Hardcover, Softcover / Medizin/Pharmazie; Pharmakologie; Verstehen; Amino acid; Bioactive proteins; Drug development; Peptide chemistry; Peptide sequences; Pharmacology; Medicinal Chemistry; Medizinische Chemie, Pharmazeutische Chemie; BC

Peptide-Based Drug Design: Here and Now.- Strategies for the Discovery, Isolation, and Characterization of Natural Bioactive Peptides from the Immune System of Invertebrates.- Sequence Analysis of Antimicrobial Peptides by Tandem Mass Spectrometry.- The Spot Technique: Synthesis and Screening of Peptide Macroarrays on Cellulose Membranes.- Analysis of A? Interactions Using ProteinChip Technology.- NMR in Peptide Drug Development.- Molecular Dynamics Simulations of Peptides.- Short Linear Cationic Antimicrobial Peptides: Screening, Optimizing, and Prediction.- Investigating the Mode of Action of Proline-Rich Antimicrobial Peptides Using a Genetic Approach: A Tool to Identify New Bacterial Targets Amenable to the Design of Novel Antibiotics.- Serum Stability of Peptides.- Preparation of Glycosylated Amino Acids Suitable for Fmoc Solid-Phase Assembly.- Synthesis of O-Phosphopeptides on Solid Phase.- Peptidomimetics: Fmoc Solid-Phase Pseudopeptide Synthesis.- Synthesis of Toll-Like Receptor-2 Targeting Lipopeptides as Self-Adjuvanting Vaccines.- Synthesis of a Multivalent, Multiepitope Vaccine Construct.- Cysteine-Containing Fusion Tag for Site-Specific Conjugation of Therapeutic and Imaging Agents to Targeting Proteins.
Presents full coverage of peptide-based drug development arranged in a sequential order as the leads proceed through the preclinical pipeline Describes innovative and unusual technologies Special focus on peptide drugs in infectious diseases Includes contributions from international leaders in their respective fields Provides a balance of scientific rigor, potential reproducibility and drug development economics

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