Transient Receptor Potential Channels - nuovo libro

EAN (ISBN-13): 9789400702653
ISBN (ISBN-10): 9400702655
Anno di pubblicazione: 2011
Editore: Springer-Verlag
1095 Pagine
Lingua: eng/Englisch

Libro nella banca dati dal 2012-05-03T23:27:48+02:00 (Zurich)
Pagina di dettaglio ultima modifica in 2023-06-19T06:12:32+02:00 (Zurich)
ISBN/EAN: 9789400702653

ISBN - Stili di scrittura alternativi:
94-007-0265-5, 978-94-007-0265-3
Stili di scrittura alternativi e concetti di ricerca simili:
Autore del libro : islam, schiller
Titolo del libro: transient, potential

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Dati dell'editore

Autore: Md. Shahidul Islam
Titolo: Advances in Experimental Medicine and Biology; Transient Receptor Potential Channels
Editore: Springer; Springer Netherland
1095 Pagine
Anno di pubblicazione: 2011-02-04
Dordrecht; NL
Lingua: Inglese
213,99 € (DE)
220,00 € (AT)
236,00 CHF (CH)
Available
XXIV, 1096 p.

EA; E107; eBook; Nonbooks, PBS / Medizin/Nichtklinische Fächer; Medizinische Forschung; Verstehen; Electrophysiology; Ion channels; Sensory signalling; TRP channels; Transient receptor potential channels; B; Biomedical Research; Life Sciences; Human Physiology; Biomedical and Life Sciences; Biowissenschaften, allgemein; Physiologie; BB

Contents. Preface. 1. Structural biology of TRP channels. 2. Functional and structural studies of TRP channels heterologously expressed in budding yeast. 3. Natural product ligands of TRP channels. 4. Synthetic modulators of TRP channel activity. 5. Study of TRP channels by automated patch clamp systems. 6. TRPC2: of mice but not men. 7. TRPM1: New trends for an old TRP. 8. The non-selective monovalent cationic channels TRPM4 and TRPM5. 9. TRPM7, the Mg2+ inhibited channel and kinase. 10. TRPM8 in health and disease: cold sensing and beyond. 11. TRPML1. 12. TRPML2 and the evolution of mucolipins. 13. The TRPML3 channel: from gene to function. 14. TRPV5 and TRPV6 in transcellular Ca2+ transport: regulation, gene duplication, and polymorphisms in African populations. 15. The TRPV5 promoter as a tool for generation of transgenic mouse models. 16. TRPP channels and polycystins. 17. TRP channels in yeast. 18. C. elegans TRP channel. 19. Investigations of TRP channel function in vivo using frog and zebrafish model systems. 20. TRP channels in parasites. 21. Receptor signaling integration by TRP channelsomes. 22. Gating mechanisms of canonical transient receptor potential channel proteins:role of phosphoinositols and diacylglycerol. 23. The TRPC ion channels: association with Orai1 and STIM1 proteins and participation in capacitative and non-capacitative calcium entry. 24. Contribution of TRPC1 and Orai1 to Ca2+ entry activated by store depletion. 25. Primary thermosensory events in cells. 26. ThermoTRP channels: biophysics of polymodal receptors. 27. Complex regulation of TRPV1 and related thermoTRPs: implications for therapeutic intervention. 28. Voltage sensing in thermo TRP channels. 29. TRP channels as mediators of oxidative stress. 30. Regulation of TRP signaling by ion channel translocation between cell compartments. 31. Emerging roles of canonical TRP channels in neuronal function. 32. TRP channels and neural persistent activity. 33. Role of TRP channels in pain sensation. 34. TRPV1: a therapy target that attracts the pharmaceutical interests. 35. Expression and function of TRP channels in liver cells. 36. Expression and physiologial roles of TRP channels in smooth muscle cells. 37. TRPM channels in the vasculature. 38. Molecular expression and functional role of canonical transient receptor potential channels in airway smooth muscle cells. 39. TRP channles in skeletal muscle: gene expression, function and implication for disease. 40. TRP Channels in vascular endothelial cells. 41. TRP channels in the cardiopulmonary vasculature. 42. TRP channels of islets. 43. Multiple roles for TRPs in the taste system: not your typical TRPs. 44. Roles of transient receptor potential proteins (TRPs) in epidermal keratinocytes. 45. TRP channels in urinary bladder mechanosensation. 46. The role of TRP ion channels in testicular function. 47. TRP channels in female reproductive organs and placenta. 48. Oncogenic TRP channels. 49. TRPV channels in tumor growth and progressio. 50. The Role of Transient Receptor Potential Channels in Respiratory Symptoms and athophysiology. 51. TRP channels and psychiatric disorders. 52. Transient receptor potential genes and human inherited disease.
A gold-mine for ion channel researchers and electro-physiologists A must read for cell and molecular biologists A mile stone in molecular medicine A must read drug discovery A must read for cancer researchers, neuroscientists and diabetes researchers